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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF5C
All Species:
30.3
Human Site:
S458
Identified Species:
47.62
UniProt:
O60282
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60282
NP_004513.1
957
109495
S458
D
Q
D
E
L
L
A
S
T
R
R
D
Y
E
K
Chimpanzee
Pan troglodytes
XP_525938
860
98662
Q417
D
K
T
R
A
N
E
Q
L
T
D
E
L
A
Q
Rhesus Macaque
Macaca mulatta
XP_001082054
860
98340
Q417
D
K
T
R
A
N
E
Q
L
T
D
E
L
A
Q
Dog
Lupus familis
XP_533351
955
109129
S457
D
Q
D
E
L
L
A
S
T
R
R
D
Y
E
K
Cat
Felis silvestris
Mouse
Mus musculus
P28738
956
109222
S457
D
Q
D
E
L
L
A
S
T
R
R
D
Y
E
K
Rat
Rattus norvegicus
Q6QLM7
1027
116897
S458
D
Q
E
E
L
L
V
S
T
R
G
D
N
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508129
965
109909
S462
D
Q
E
E
L
L
A
S
T
R
R
D
Q
D
N
Chicken
Gallus gallus
Q90640
1225
138905
Q562
Q
L
E
P
I
Q
S
Q
Y
Q
T
N
I
K
D
Frog
Xenopus laevis
Q91784
1226
138905
E559
Q
L
E
P
I
Q
S
E
Y
L
N
N
I
K
H
Zebra Danio
Brachydanio rerio
NP_001116747
985
113653
S454
D
Q
D
E
L
L
A
S
T
R
R
D
Y
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17210
975
110381
N478
E
Q
E
E
L
I
A
N
A
R
R
E
Y
E
T
Honey Bee
Apis mellifera
XP_395236
988
112484
T479
E
Q
A
E
L
I
A
T
A
R
R
E
Y
E
K
Nematode Worm
Caenorhab. elegans
P34540
815
91875
S395
D
S
A
Q
M
A
V
S
E
V
S
G
G
S
T
Sea Urchin
Strong. purpuratus
P35978
1031
117504
S449
E
Q
E
E
L
L
S
S
M
Q
R
D
Y
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
A460
E
K
E
S
I
A
A
A
A
E
R
Q
L
R
E
Conservation
Percent
Protein Identity:
100
89.8
85.5
98.3
N.A.
98
69.8
N.A.
75.2
26.3
24.8
76.8
N.A.
62
63.2
45.3
61.4
Protein Similarity:
100
89.8
86.4
98.9
N.A.
99.1
81.6
N.A.
86.4
45.3
45.5
86.9
N.A.
77.6
77.9
61.3
74.7
P-Site Identity:
100
6.6
6.6
100
N.A.
100
73.3
N.A.
73.3
0
0
100
N.A.
53.3
60
13.3
60
P-Site Similarity:
100
26.6
26.6
100
N.A.
100
80
N.A.
86.6
40
33.3
100
N.A.
86.6
86.6
26.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
31.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
52.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
0
14
14
54
7
20
0
0
0
0
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
60
0
27
0
0
0
0
0
0
0
14
47
0
7
7
% D
% Glu:
27
0
47
60
0
0
14
7
7
7
0
27
0
54
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
7
7
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
20
14
0
0
0
0
0
0
14
0
0
% I
% Lys:
0
20
0
0
0
0
0
0
0
0
0
0
0
14
40
% K
% Leu:
0
14
0
0
60
47
0
0
14
7
0
0
20
0
7
% L
% Met:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
14
0
7
0
0
7
14
7
0
7
% N
% Pro:
0
0
0
14
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
14
60
0
7
0
14
0
20
0
14
0
7
7
0
14
% Q
% Arg:
0
0
0
14
0
0
0
0
0
54
60
0
0
7
0
% R
% Ser:
0
7
0
7
0
0
20
54
0
0
7
0
0
7
0
% S
% Thr:
0
0
14
0
0
0
0
7
40
14
7
0
0
0
14
% T
% Val:
0
0
0
0
0
0
14
0
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
14
0
0
0
47
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _